I think it depends on the ending you get or whatever faction you side with. For example, they'd get wiped out eventually by NCR, either wiped out or assimilated into the Legion, or be made a family of the strip by House/Yes-man if they ever decide to expand. House did that with the original families.

In theory, the Fiends could be forced to abandon their ways of excessive drug use, or at least minimize it. The White Glove Society were forced to give up cannibalism and that seemed a pretty integral part of their community back when they were tribal, like how drug use is a pretty integral part of the Fiends. Oh, and the murdering...

When you say they'd be wiped out by the NCR or the Legion, does that mean their theoretical leader, the Courier, would be unable to stop their destruction at the hands of the other factions?

i only have one thing to say in this subject "violent pleasures have violent ends"

aye some shakespeare reference right under you nose m8's

Meth is a Hell of a drug :

But seriously the fiends would never organize even with the Courier and Fiend Leaders like Motor Runner or Cook Cook
Sooner or later their fates were sealed. Wither it was Legion or NCR or House the Fiends would be eradicated. Like the Great Khans the Fiends would have been massacred by whom ever won at Hoover Dam. Not to mention how even with Motor Runner leading things from Vault 3 currently the fiends are so strung out on drugs they are almost impossible to lead in a organized manner. I don't believe the courier could get them to work together without getting them off the drugs.
Raiders from Fallout 3 would be easier than Fiends. At least the Raiders have Evergreen Mills.

The courier would have to go the yes man route to have proper firepower against any organized faction since the main army is junkie raiders. They obviously dont produce anything to sustain themselves (They have to rely on drug runners like Great Khans) and dont seem to be interested in that (Too drugged up lol). Someone is gonna put them down, i dont see any allies for the fiends with their reputation

blahblahblah wrote:

The courier would have to go the yes man route to have proper firepower against any organized faction since the main army is junkie raiders.

Yeah, that was pretty much my assumption; a fully empowered Courier trying to use the Fiends.
The NCR has been purged from the Mojave and nuked, the Legion -- the same. House is gone. There's no one left to wipe out the fiends.

So now what if they're all now dosed with Fixer by a canny Courier?

Fiends are sadly the poor victims of other more powerful peoples' power play. Whatever tribal customs they once had have been annihilated by the Legion's support of their drug epidemic and funded proxy war, and the NCR fully intends to wipe them out (Great Khan-style I might add) once given the chance. They're a blight on Mr House's vision of a pre-war Vegas, so I imagine that securitron army will quickly be rolling down south after Hoover Dam is reclaimed.

Maybe an independent Vegas under the Courier would treat them differently? I don't know, I think it's for the best that their leaders are taken out of the picture, and whatever Fiends left alive after that are given the chance to escape the life and rehabilitate Razz-style. I imagine a lot of them would stick together and either migrate elsewhere (again, similar to the Khans) or try to integrate into Vegas.

I dislike the fact that more details aren't given into the Fiends' personal lives. With the skull helmets and various bases of operations, they're obviously a tribe in their own right, but the game wanted the Fallout 3-style junkie raiders as cannon-fodder so there they are. I'd love more characters with humanised stories, more details into how they operate socially, their drug and slave trades, and seriously, where are their kids and elderly?